6DP3DT
Progesterone, Bloating, and Pinopodes
It's been a bit of a day - my abdomen is all bloated and distended. A quick check with Dr. Google says that bloating is normal for progesterone. Lovely. I don't recall having this effect so much before, but perhaps it's mostly due to my increasing myself from 200 to 400mg a day of the stuff.
I wish I could say I've had huge twinges indicating something's going on down there, but I know just about anything I'm feeling is due to the progesterone at this point.
I found a rather interesting article tonight on how endometrial pinopodes (little structures that blasts adhere to) show up earlier in stimulated cycles (1 to 2 days earlier) than they do in natural cycles and might be the reason for repeated implantation failure in some patients. So put into laymans terms, if you put in blasts that are ready to attach but your pinopodes are on the way out or area already gone, you're screwed. There's nothing for them to attach to. I haven't figured out if there is a way to delay pinopode formation...but surely someone's studied this. I wonder (bet?) that this is part of my problem. It feels intuitively right. I suspect that perhaps delaying progesterone a bit could help my lining "catch the wave", to use Dr. Harvey Kliman's term (however out of context - apologies to Dr. Kliman for the liberty).
Anyways, I've got enough progesterone to last me through Tuesday but I just don't know how I'm going to stand this bloating. I seriously look 3 or 4 months pregnant, easily. Don't I wish?
Labels: IVF4 Take 4, The Hell that IVF Is
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Progesterone, Bloating, and Pinopodes"