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Saturday, July 10, 2010

And our RE's say our uteri are sticky like a peanut butter sandwich?

I've been doing a lot of reading while I heal from my surgery a week ago Wednesday. I feel a bit better each day but had a setback on Friday when it seemed I had a mild case of food poisoning. I ran a bit of a low fever, slept for about 36 hours, and today I'm feeling perky again. I am still experiencing some cramping on the right side, where I am told the bulk of my adhesions were at (and this is what Dr. Persian explains why I've had ongoing pain on the right side). Add in the appendectomy that they did and it's no wonder my right side is aching.

In my off time, I am trying to find a surrogate (no small feat), prepare for my meeting with Dr. Check at Cooper (which is in NJ, a state that hasn't completely banned surrogacy), and I'm trying to find out if there's anything concrete to the link between adenomyosis and infertility.

From, "Adenomyosis: New Knowledge Is Generating New Treatment Strategies: Adenomyosis and Fertility":

"The first experimental evidence that adenomyosis may cause infertility comes from Barrier et al. [50] In 2004, they published a case–control study in a population of captive baboons and found that adenomyosis was associated with the presence of lifelong infertility (odds ratio: 20.6). Their conclusion was that the condition is strongly associated with primary infertility in baboons, even in the absence of coexisting endometriosis."


I wonder if lupron depot therapy offers any relief for adenomyosis as it does for endometriosis? Something I'll be researching. In one of my many adenomyosis articles I came across a mention to JZ contractions, which seem to be correlated to failed transfers.

On this particular subject, I found in subsequent reading that our uteri actually elicit these contractions, called JZ (junction zone) contractions, which seem to kick off when something foreign (ie, a catheter) is put into our uterus by way of the cervix or when a tenaculum is affixed to our cervixes. Ladies, if your RE has ever assured you that your embryos aren't going to slide down your leg after a transfer ... please point him (or her) at this article.

Junctional zone contractions and embryo transfer: is it safe to use a tenaculum?
http://humrep.oxfordjournals.org/cgi/reprint/14/9/2367.

This is an older article, from 1999. But it starts off with,

"Embryo transfer is one of the most critical steps affecting the success rate of in-vitro fertilization (IVF) and has changed little since IVF was first described.

Unless something has changed in embryo transfer research in the last 11 years this article may very well still be current.

Then, go to the 2nd page and locate the paragraph on the right that begins with, "The ability of fundo-cervical contractions to move the mock embryo towards the cervix...".

Read and be stunned.

All I know is that my paranoid fears of losing my embryos with transfer aren't all that unjustified. They do say that a surgical transfer that bypasses the cervix is more successful. Interesting indeed, but where on earth does one get a surgical transfer. This article is 1999 though, and perhaps it's something that died off in the late 1990's?

Anyways, back to reading more and trying to figure out this mystery called adenomyosis.

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Comments on "And our RE's say our uteri are sticky like a peanut butter sandwich?"

 

Anonymous Jamie said ... (9:58 PM) : 

Fascinating! Maybe that is why post-transfer acu is important, to calm down the uterus? As well as the valium.

Good luck with your Dr. Check consult. He is a character and I'm interested to hear how it goes.

 

Anonymous musicmakermomma said ... (6:17 PM) : 

So sorry to hear about your latest diagnosis - would have been nice to know this, say, YEARS ago! But hopefully you can press forward now. Are the docs you are working with agreeable to you harvesting and stockpiling eggs? I am thinking of you and hoping so hard.

 

Blogger linda said ... (6:26 PM) : 

Hi MMM!

Yes, it would have been great to have known this years ago. I agree. Especially since I had a lap back in 2006 by a doctor that actually talked me out of seeing the surgeon that did my recent surgery. She totally missed the diagnosis of adenomyosis. Ugh.

So far the docs at CU in NYC are refusing to freeze my eggs due to my age. So I am looking at NYU and also at Cooper in NJ. I am sorta stuck with where my insurance will cover (ie, Aetna). I'd like to stockpile embryos and then do a surrogate transfer in California. I am talking to a gal in NorCal tonight in fact!! I am excited to secure a GS and get this ball rolling. :)

I miss your posts. How are you?

 

Blogger Adele said ... (9:46 AM) : 

I've actually never heard of a surgical transfer (so, they go in differently? Like a keyhole thing?) and so I'll be very interested to hear if this method of transfer was continued/pursued.

Knowledge is power. And you are arming yourself well and truly. This can only mean good things. Good luck with your consult and, especially, with tracking down a surrogate!!!

 

Anonymous musicmakermomma said ... (8:54 PM) : 

Sorry I've been MIA lately, I just feel like I've kinda said everything before...but I expect I will get with it again soon since our final attempt is (supposedly) happening in August.

Glad you have some leads - Wonder if you could buy yourself a deepfreeze! So much red tape, hoping for you.

 

Blogger linda said ... (11:06 PM) : 

MMM,

Don't be concerned with being verbose, unique, or anything. Sometimes blogging equates to venting or ranting or just making a testament to what has gone on in your IF journey at that time. :)

I had a great meeting with Dr. Ch3ck at C@@per Clinic in NJ today. I have so much to write about when I get a chance.

Hugs,
Linda

 

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